An Evaluation of Three Hydrophylic Ointments in Skin Conductance Monitoring

INTRODUCTION

The purpose of the research project was to evaluate the effectiveness of three different electrolyte media used for electrodermal recordings. The specific aims for this project were to determine which of three compounds, differing only in the base medium, provided optimal skin conductance monitoring, did not disrupt the skin integrity, and maintained electrode effectiveness for a minimum of a 24 hours of use.

METHODOLOGY

The objectives of the project were met using a variety of techniques. First, a sample of 3 physically active young adult women and 3 perimenopausal women wore three separate electrodes approximately 1 1/2 inches below the clavicle four inches apart. For this aspect of the study, skin was assessed prior to application of the electrodes and at completion of the 24-hours of wear. In addition, participants were surveyed regarding any participant identified issues with the electrodes such as itching or leakage of the media. The two most effective electrode media in minimizing user discomfort, skin irritation, and electrode leakage were then used for phase 2 of the project.

In Phase 2, participants wore the Biolog® skin conductance monitor for a 24- hour period, using electrodes prepared with one of the electrolyte media. This allowed for evaluation of the skin conductance levels of different electrolyte media. The Biolog® monitor is an ambulatory skin conductance monitor that is worn by the participant. The Biolog® required EKG leads and an electrolyte gel to detect the skin conductance during menopausal hot flushes. Researchers have used Unibase® cream as the base medium for production of this electrolyte gel. Recently, production of this cream has been discontinued. The overall objective of the project was to identify an effective replacement medium.

SCHOLAR RESPONSIBILITIES

As a university scholar, I was very involved in every aspect of this project. Initially, I was assigned to determine the most effective manner of mixing the electrolyte media. I had the opportunity to work in a pharmacy lab and observe graduate students conducting various experiments. During Phase 1, I was responsible for assessing the effects of each electrolyte media on the volunteers and recording my findings. During Phase 2, I had to become familiar with operating