Nicotine as an Aromatase Inhibitor

Nicotine works in two ways to lower estrogen levels. First it is an anti-aromatase like arimadex. Nicotine has been shown to inhibit the conversion of androstenedione and testosterone into estrogen in a study by the University of Utah School of medicine. Also unlike novadex or clomid nicotine is a true anti estrogen and not just an estrogen blocker. By this I mean that nicotine actually speeds up the degradation of blood estrogen levels. So nicotine causes a reduction in estrogen production and also decreases existing estrogen levels.

Regulation of hormone levels

When Nicotine is used on a daily basis it stabilizes the Adrenal hormones by acting on the Hypothalamus, which affects the pituitaries release of regulating hormones and increases GH release. This keeps various hormone levels stable during times of depression, or stress. That is why a smoker can have a cigarette in the morning to wake up and one at night to help relax.

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